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Langerhans cells are up to the job, they just need a
chance

Researchers found that Langerhans cells (LCs) play a crucial role
in mucocutaneous acute guest-versus-host disease (aGVHD). Their
experiments in mice showed that when the LCs of a recipient were
depleted, the formation of mucocutaneous lesions was enhanced
because the infiltration of CD8+ T cells was inhibited. Their
findings have significant implications for improving blood stem
cell transplantation treatments and clinical outcomes for patients.
Researchers found that Langerhans cells (LCs) play a crucial role
in mucocutaneous acute guest-versus-host disease (aGVHD). Their
experiments in mice showed that when the LCs of a recipient were
depleted, the formation of mucocutaneous lesions was enhanced
because the infiltration of CD8+ T cells was inhibited. Their
findings have significant implications for improving blood stem
cell transplantation treatments and clinical outcomes for patients.

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